For many people, grit – the perseverance and passion for long-term goals – is a virtue. It is also a key ingredient in overcoming challenges, achieving success and maintaining resilience.
Studies have linked grit with success in goal attainment, improved psychological well-being and increased life satisfaction.
But despite conventional narratives equating this type of psychological persistence with well-being, brain research is beginning to show that mustering grit in the face of adversity may also have some unexpected detrimental effects – particularly for communities that are already under chronic stress.
As a behavioral scientist studying Alzheimer’s disease and brain health in Black communities, I use techniques such as brain activity monitoring to examine risk factors and early signs of cognitive decline. My research along with other work is beginning to uncover that pushing through can create a level of stress that actually taxes brain health.
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The paradox of grit, active coping and brain health
Grit has become a central idea in psychology. Researchers have mainly focused on its positive features, describing it as a quality that helps people work hard, stay strong during tough times and keep trying even when things are difficult. Active coping is a similar concept defined as addressing problems directly and actively seeking solutions. Studies have linked it to lower stress, better health and feeling more in control.
Traits such as grit and active coping are strategies used to manage stress, and they are traditionally seen as protective factors for well-being.
But perseverance may also come with risks that can contribute to poor brain health outcomes. Consider the concept of John Henryism, developed by an epidemiologist named Sherman James in the 1970s.
John Henryism is a coping strategy characterized by persistent, high-effort striving in response to chronic stressors, particularly among marginalized groups. It is named after the legendary African American folk hero John Henry, who worked himself to death in a contest against a steam-powered drill. In the folk tale, John Henry exemplifies how people may engage in prolonged, high-effort coping, often at the expense of their health. James used the folklore to symbolize the relentless effort to overcome structural and systemic barriers.
For example, imagine someone in their early 40s who works two physically demanding jobs to support their family and prevent homelessness. They believe relentless effort is the only path to stability, despite experiencing chronic fatigue and pain. Over time, this sustained strain may lead to high blood pressure, stroke and depression – all of which have been linked to cognitive decline.
Ken Thomas via Wikimedia Commons
John Henryism has been linked to negative health outcomes, including increased risks of hypertension, cardiovascular disease and early mortality. It has also been linked to the risk of poor brain health.
Perseverance and the risk of cognitive impairment
My colleagues’ and my recent work supports the idea that high-effort coping such as grit can contribute to neurocognitive wear and tear. Being constantly under stress can essentially overwork certain parts of the brain. This damage can build up to make it harder for the brain to learn new things, remember information and stay sharp as a person gets older.
In our study published in January 2025, we asked 158 Black men living in the U.S. to participate in an online survey. The survey measured grit by asking how much participants agreed with statements like “I finish whatever I begin.” It also asked participants to report how often they experienced episodes of memory loss and confusion and to rank whether these episodes were becoming more frequent.
We found that men with higher levels of grit reported greater cognitive difficulties such as trouble concentrating, forgetfulness and feeling mentally fatigued, despite their strong motivation to persevere. While our study couldn’t determine whether grit causes these difficulties, it raises important questions about whether sustained, high-effort coping might come at a cognitive cost over time.
A concept called allostatic load provides one possible explanation for the link between perseverance and the cognitive decline we observed in our study. Allostatic load is the wear and tear on the body that builds up over time due to dealing with stress.
I believe individuals who push through adversity against all odds may experience allostatic load more acutely. Their persistent coping could intensify physiological strain over time, contributing to earlier onset of cognitive decline. This explanation aligns with previous work, which has shown that prolonged exposure to stress can accelerate cognitive decline and negatively affect memory and executive function.
Facing frequent stressors such as racism, discrimination, economic challenges and limited access to health care with intense levels of perseverance may encourage people to push through these challenges without adequate recovery. That can cause chronic stress that damages brain health.
Continuously exerting mental and emotional effort without relief may also result in cognitive overload and diminish people’s ability to sustain mental resilience. This burden accelerates brain aging and increases the risk of cognitive decline.
Unlike the occasional stress of meeting a deadline or completing a difficult project, this type of overexertion is more like waking up every day already exhausted, yet pushing through multiple jobs, financial worries and family responsibilities with little rest or support. Over time, this constant mental strain may wear down the brain’s ability to recover and maintain clarity, even when the person appears outwardly resilient.
Rethinking perseverance
Researchers are beginning to build a more nuanced understanding of perseverance that challenges the conventional wisdom that it is always beneficial. This perspective also redefines the notion of strength in the face of adversity.
In this more realistic definition, perseverance can include self-care and rest. Knowing when to take a break or prioritize self-care is a practical strategy for maintaining cognitive health in the face of challenges.
Also, practices such as meditation, deep breathing and guided relaxation can help regulate stress responses and reduce cognitive strain. And beyond personal resilience, leaning on social support and meaningful connections can be just as crucial for long-term brain health.
